Extracellular Matrix Rigidity Promotes Invadopodia Activity
نویسندگان
چکیده
منابع مشابه
Extracellular Matrix Rigidity Promotes Invadopodia Activity
Invadopodia are actin-rich subcellular protrusions with associated proteases used by cancer cells to degrade extracellular matrix (ECM) [1]. Molecular components of invadopodia include branched actin-assembly proteins, membrane trafficking proteins, signaling proteins, and transmembrane proteinases [1]. Similar structures exist in nontransformed cells, such as osteoclasts and dendritic cells, b...
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ژورنال
عنوان ژورنال: Current Biology
سال: 2008
ISSN: 0960-9822
DOI: 10.1016/j.cub.2008.07.090